Publications

  1. Patel W, Moore PJ, Sassano MF, Lopes-Pacheco M, Aleksandrov AA, Amaral MD, Tarran R, Gray MA (2019) Increases in cytosolic Ca2+ induce dynamin- and calcineurin-dependent internalisation of CFTR. Cell Mol Life Sci. 76(5):977-994. [https://doi.org/10.1007/s00018-018-2989-3] [PubMed]
  2. Vaz Dias F, Serrazina S, Vitorino M, Marchese D, Heilmann I, Godinho M, Rodrigues M, Malhó R (2019) A role for diacylglycerol kinase 4 in signalling crosstalk during Arabidopsis pollen tube growth. New Phytol. 222(3):1434-1446. [https://doi.org/10.1111/nph.15674] [PubMed]
  3. Loureiro CA, Santos JD, Matos AM, Jordan P, Matos P, Farinha CM, Pinto FR (2019) Network Biology Identifies Novel Regulators of CFTR Trafficking and Membrane Stability. Front Pharmacol. 10:619. [https://doi.org/10.3389/fphar.2019.00619] [PubMed]
  4. Santos JD, Canato S, Carvalho AS, Botelho HM, Aloria K, Amaral MD, Matthiesen R, Falcao AO, Farinha CM (2019) Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum. Cells. 8(4): E353. [https://doi.org/10.3390/cells8040353] [PubMed]
  5. Palma E, Botelho HM, Morais GR, Rodrigues I, Santos IC, Campello MPC, Raposinho P, Belchior A, Gomes SS, Araújo MF, Correia I, Ribeiro N, Gama S, Mendes F, Paulo A (2019) Unravelling the antitumoral potential of novel bis(thiosemicarbazonato) Zn(II) complexes: structural and cellular studies. J Biol Inorg Chem. 24(1):71-89. [https://doi.org/10.1007/s00775-018-1629-6] [PubMed]
  6. Awatade NT, Ramalho S, Silva IAL, Felício V, Botelho HM, de Poel E, Vonk A, Beekman JM, Farinha CM, Amaral MD (2019) R560S: A class II CFTR mutation that is not rescued by current modulators. J Cyst Fibros. 18(2):182-189. [https://doi.org/10.1016/j.jcf.2018.07.001] [PubMed]
  7. Dias JNR, Aguiar SI, Pereira DM, André AS, Gano L, Correia JDG, Carrapiço B, Rütgen B, Malhó R, Peleteiro C, Goncalves J, Rodrigues CMP, Gil S, Tavares L, Aires-da-Silva F (2018) The histone deacetylase inhibitor panobinostat is a potent antitumor agent in canine diffuse large B-cell lymphoma. Oncotarget . 9(47):28586-28598. [https://doi.org/10.18632/oncotarget.25580] [PubMed]
  8. Casimiro MH, Gomes SR, Rodrigues G, Leal JP, Ferreira LM (2018) Chitosan/Poly(vinylpyrrolidone) Matrices Obtained by Gamma-Irradiation for Skin Scaffolds: Characterization and Preliminary Cell Response Studies. Materials (Basel). 11(12):E2535. [https://doi.org/10.3390/ma11122535] [PubMed]
  9. Lérias JR, Pinto MC, Botelho HM, Awatade NT, Quaresma MC, Silva IAL, Wanitchakool P, Schreiber R, Pepperkok R, Kunzelmann K, Amaral MD (2018) A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic. Biochim Biophys Acta Mol Cell Res. 1865(2):421-431. [https://doi.org/10.1016/j.bbamcr.2017.11.009] [PubMed]
  10. Olivença DV, Uliyakina I, Fonseca LL, Amaral MD, Voit EO, Pinto FR (2018) A Mathematical Model of the Phosphoinositide Pathway. Sci Rep. 8(1):3904. [https://doi.org/10.1038/s41598-018-22226-8] [PubMed]
  11. Sampaio-Pinto V, Rodrigues SC, Laundos TL, Silva ED, Vasques-Nóvoa F, Silva AC, Cerqueira RJ, Resende TP, Pianca N, Leite-Moreira A, D’Uva G, Thorsteinsdóttir S, Pinto-do-Ó P, Nascimento DS (2018) Neonatal Apex Resection Triggers Cardiomyocyte Proliferation, Neovascularization and Functional Recovery Despite Local Fibrosis. Stem Cell Reports. 10(3):860-874. [https://doi.org/10.1016/j.stemcr.2018.01.042] [PubMed]
  12. Camelo C, Vilas-Boas F, Cepeda AP, Real C, Barros-Martins J, Pinto F, Soares H, Marinho HS, Cyrne L (2017) Opi1p translocation to the nucleus is regulated by hydrogen peroxide in Saccharomyces cerevisiae. Yeast. 34(9):383-395. [https://doi.org/10.1002/yea.3240] [PubMed]
  13. Gomes S, Rodrigues G, Martins G, Henriques C, Silva JC (2017) Evaluation of nanofibrous scaffolds obtained from blends of chitosan, gelatin and polycaprolactone for skin tissue engineering. Int J Biol Macromol. 102:1174-1185. [https://doi.org/10.1016/j.ijbiomac.2017.05.004] [PubMed]
  14. Gomes de Almeida P, Pinheiro GG, Nunes AM, Gonçalves AB, Thorsteinsdóttir S (2016) Fibronectin assembly during early embryo development: A versatile communication system between cells and tissues. Dev. Dyn. 245(4):520-35. [https://doi.org/10.1002/yea.3240] [PubMed]
  15. Gonçalves AB, Thorsteinsdóttir S, Deries M (2016) Rapid and simple method for in vivo ex utero development of mouse embryo explants. Differentiation. 91(4-5):57-67. [https://doi.org/10.1016/j.diff.2015.12.002] [PubMed]
  16. Igreja S, Clarke LA, Botelho HM, Marques L, Amaral MD (2015) Correction of a Cystic Fibrosis Splicing Mutation by Antisense Oligonucleotides. Hum. Mutat. 37(2):209-15. [https://doi.org/10.1002/humu.22931] [PubMed]
  17. Botelho HM, Uliyakina I, Awatade NT, Proença MC, Tischer C, Sirianant L, Kunzelmann K, Pepperkok R, Amaral MD (2015) Protein traffic disorders: an effective high-throughput fluorescence microscopy pipeline for drug discovery. Sci. Rep. 5:9038. [https://doi.org/10.1038/srep09038] [PubMed]
  18. Saavedra L, Catarino R, Heinz T, Heilmann I, Bezanilla M, Malhó R (2015) Phosphatase and Tensin Homolog Is a Growth Repressor of Both Rhizoid and Gametophore Development in the Moss Physcomitrella patens. Plant Physiol. 169, 2572–86. [https://doi.org/10.1002/yea.3240] [PubMed]